Figure 2: Effect of Salvia miltiorrhiza extract on melanogenesis in B16F10 cells. Melanin content in B16F10 melanoma cells was determined after exposure to drugs at various concentrations for 72 h. (a) Effect of Salvia miltiorrhiza extract on melanin production in B16F10 cells. (b) Morphology of B16F10 cells treated with Salvia miltiorrhiza extract. The result shown are expressed as a mean value ± standard error of the mean of three independent experiments and the data were analyzed by one-way analysis of variance followed by post hoc Tukey's test. (*P < 0.05 vs. control group).