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  Indian J Med Microbiol
 

Figure 2: (a) The biopsy specimen from the right forearm reveals epidermal hyperplasia with a lichenoid lymphocytic infiltrate in the upper dermis (H and E, scanning view). (b) The epidermal hyperplasia is characterized by saw-tooth appearance and wedge-shaped hypergranulosis (H and E, ×200). (c) To the right side of the section, the epidermis is atrophic with vacuolar interface change (H and E, ×200). (d) Focally, there are lymphocytic infiltrates around the hair follicle (H and E, ×100). (e) Periodic acid–Schiff staining highlights the thickened basement membrane zone (×400). (f) Immunohistochemistry study of CD123 highlights plasmacytoid dendritic cells in the dermal infiltrate (×200). (g) Direct immunofluorescence study reveals immunoglobulin M-positive cytoid bodies, and (h) clusters of C3-positive cytoid bodies in the papillary dermis (×400)

Figure 2: (a) The biopsy specimen from the right forearm reveals epidermal hyperplasia with a lichenoid lymphocytic infiltrate in the upper dermis (H and E, scanning view). (b) The epidermal hyperplasia is characterized by saw-tooth appearance and wedge-shaped hypergranulosis (H and E, ×200). (c) To the right side of the section, the epidermis is atrophic with vacuolar interface change (H and E, ×200). (d) Focally, there are lymphocytic infiltrates around the hair follicle (H and E, ×100). (e) Periodic acid–Schiff staining highlights the thickened basement membrane zone (×400). (f) Immunohistochemistry study of CD123 highlights plasmacytoid dendritic cells in the dermal infiltrate (×200). (g) Direct immunofluorescence study reveals immunoglobulin M-positive cytoid bodies, and (h) clusters of C3-positive cytoid bodies in the papillary dermis (×400)