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  Indian J Med Microbiol
 

Figure 2: (a and b) Histopathology showed hyperkeratosis and mild acanthosis. Note the dilated eccrine gland (hematoxylin and eosin, [a] ×40, [b] ×100). (c) Immunohistochemistry analysis showed a marked reduction in CD1a-positive Langerhans cells in the epidermis (×100), compared to (d) the control skin specimen (×100). (e) Immunohistochemistry stain showed near absence of epidermal S100-positive Langerhans cells (× 100) compared to (f) the control skin specimen (×100)

Figure 2: (a and b) Histopathology showed hyperkeratosis and mild acanthosis. Note the dilated eccrine gland (hematoxylin and eosin, [a] ×40, [b] ×100). (c) Immunohistochemistry analysis showed a marked reduction in CD1a-positive Langerhans cells in the epidermis (×100), compared to (d) the control skin specimen (×100). (e) Immunohistochemistry stain showed near absence of epidermal S100-positive Langerhans cells (× 100) compared to (f) the control skin specimen (×100)