Reliability and validity of the Chinese version of the vitiligo specific quality of life instrument (VitiQoL) Zhao H, Zhao N, Zhou B, Chen G, Wang Y, Zhang H, Lin Y, Liu H, Kundu RV, Yang B, - J Indian Prosthodont Soc

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Reliability and validity of the Chinese version of the vitiligo specific quality of life instrument (VitiQoL) Hui Zhao¹, Na Zhao², Bingni Zhou², Guo Chen³, Yaru Wang², Huimin Zhang², Yan Lin², Huaxu Liu², Roopal V Kundu⁴, Baoqi Yang² ¹ Department of Dermatology, Shandong Provincial Hospital for Skin Diseases & Shandong Provincial Institute of Dermatology and Veneorology, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan; Department of Dermatology, Dalian Children's Hospital, Dalian, China ² Department of Dermatology, Shandong Provincial Hospital for Skin Diseases & Shandong Provincial Institute of Dermatology and Veneorology, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, China ³ Department of Dermatology, Jinan Municipal Second Dermatosis Prevention and Control Hospital, Jinan, China ⁴ Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA Correspondence Address: Baoqi Yang, Shandong Provincial Hospital for Skin Diseases & Shandong Provincial Institute of Dermatology and Veneorology, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong, 250022 China Source of Support: None, Conflict of Interest: None DOI: 10.4103/ds.ds_48_20

Background: Vitiligo is an acquired, idiopathic skin disorder that can significantly affect the health-related quality of life (QoL). The vitiligo-specific QoL instrument (VitiQoL), recently developed by an American group, was found to be a reliable patient-reported outcome measure in both Brazilian and Iranian patients. Methods: The VitiQoL was initially cross-culturally adapted to Chinese through forward-backward translation. The Chinese version of the VitiQoL was then distributed to 182 vitiligo patients together with the dermatology life quality index (DLQI) and Skindex-16 questionnaire. Then, the reliability and validity of the Chinese version of the VitiQoL was assessed by statistical analysis. Results: The Chinese version of the VitiQoL showed high internal consistency (Cronbach alpha = 0.958) and test–retest reliability (intraclass correlation coefficient = 0.887). Convergent validity testing showed that the correlation coefficient for the Chinese VitiQoL and DLQI was 0.70 (P < 0.01), the Chinese VitiQoL and Skindex-16 each was 0.84 (P < 0.01), and for the Chinese VitiQoL (questions 1–15 and 16) was 0.62 (P < 0.01). Confirmatory factor analysis revealed two important factors within the VitiQoL: Participation limitation and stigma. Conclusion: The Chinese version of the VitiQoL questionnaire has sufficient reliability and validity to be used to evaluate Chinese vitiligo patients' QoL.

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