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  Indian J Med Microbiol
 

Figure (1): Clinical pictures and genetic study results. (a) Multiple whitish, slightly edematous blisters developed over the bilateral soles, especially the pressure-bearing areas in the patient (IV-2). (b) A skin biopsy was done on a linear blister on the right sole in the patient (IV-2). (c) Multiple affected family members in the pedigree indicates an autosomal dominant inheritance. (d) A heterozygous mutation p.Glu411del (c.1231_1233delGAG) in the keratin 14 gene is identified in the patient (IV-2) and his mother (III-2) by Sanger sequencing

Figure (1): Clinical pictures and genetic study results. (a) Multiple whitish, slightly edematous blisters developed over the bilateral soles, especially the pressure-bearing areas in the patient (IV-2). (b) A skin biopsy was done on a linear blister on the right sole in the patient (IV-2). (c) Multiple affected family members in the pedigree indicates an autosomal dominant inheritance. (d) A heterozygous mutation p.Glu411del (c.1231_1233delGAG) in the keratin 14 gene is identified in the patient (IV-2) and his mother (III-2) by Sanger sequencing