Close
  Indian J Med Microbiol
 

Figure 1: (a). Tremendous vulvar ulcerative lesion of a 48-year-old woman, involving the right labium majus, labium minus, and partial left labium minus, with elevated granulation tissue and mucinous discharge. (b1 and 2) Histopathological examination of the vulvar biopsy showed mild parakeratosis, mild irregular acanthosis, focal pseudoepitheliomatous hyperplasia, neutrophilic exocytosis, and diffuse heavy infiltrates of numerous plasma cells with scattered lymphocytes and eosinophils in the submucosa. (c) Immunohistochemistry study showed that the plasma cells were positive for IgG. (d) With oral and topical steroids, the vulva returned to normal appearance in 3 weeks

Figure 1: (a). Tremendous vulvar ulcerative lesion of a 48-year-old woman, involving the right labium majus, labium minus, and partial left labium minus, with elevated granulation tissue and mucinous discharge. (b1 and 2) Histopathological examination of the vulvar biopsy showed mild parakeratosis, mild irregular acanthosis, focal pseudoepitheliomatous hyperplasia, neutrophilic exocytosis, and diffuse heavy infiltrates of numerous plasma cells with scattered lymphocytes and eosinophils in the submucosa. (c) Immunohistochemistry study showed that the plasma cells were positive for IgG. (d) With oral and topical steroids, the vulva returned to normal appearance in 3 weeks