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CASE REPORT
Year : 2020  |  Volume : 38  |  Issue : 2  |  Page : 105-109

Extranodal natural killer/T-cell lymphoma, nasal type, presenting with acneiform eruptions: A previously undescribed variant


1 Department of Dermatology, Taipei Veterans General Hospital, Taipei, Taiwan
2 Department of Dermatology, Taipei Medical University – Shuang Ho Hospital, New Taipei City, Taiwan
3 Department of Dermatology, Taipei Veterans General Hospital; Department of Dermatology, Taipei Medical University – Shuang Ho Hospital, New Taipei City, Taiwan

Correspondence Address:
Dr. Han-Nan Liu
Department of Dermatology, Taipei Medical University – Shuang Ho Hospital, No. 291, Zhongzheng Road, Zhonghe District, New Taipei City 23561
Taiwan
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ds.ds_39_19

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Extranodal natural killer/T-cell lymphoma (ENKTL), nasal type, is an Epstein–Barr virus (EBV)-associated aggressive form of lymphoma that primarily involves areas outside the nasal cavity. Skin is also commonly involved resulting in a variety of skin manifestations. Here, we report an ENKTL, nasal type, in a 29-year-old male with a previously undescribed acneiform presentation. Skin biopsy revealed an angiodestructive, perivascular lymphocytic infiltration, which stained positive for CD3, CD56, and TIA-1 in various proportions. Scattered EBV-infected cells were demonstrated by in situ hybridization. The patient received chemotherapy with almost complete resolution of the skin lesions initially but later experienced flare-ups.


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