• Users Online: 533
  • Print this page
  • Email this page
CASE REPORT
Year : 2019  |  Volume : 37  |  Issue : 3  |  Page : 166-169

A case of pretibial myxedema associated with hypothyroidism and thyroid-stimulating hormone receptor antibodies


1 Department of Internal Medicine, Myongji Hospital, Hanyang University College of Medicine, Gyeonggi-do, Republic of Korea
2 Department of Dermatology, Myongji Hospital, Hanyang University College of Medicine, Gyeonggi-do, Republic of Korea
3 Department of Pathology, Myongji Hospital, Hanyang University College of Medicine, Gyeonggi-do, Republic of Korea
4 Department of Internal Medicine, Division of Endocrinology and Metabolism, Myongji Hospital, Hanyang University College of Medicine, Gyeonggi-do, Republic of Korea

Correspondence Address:
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ds.ds_51_18

Rights and Permissions

Pretibial myxedema (PTM) is an infiltrative dermopathy seen in Graves' disease. It is also infrequently associated with hypothyroidism. Here, we describe a rare case of PTM with hypothyroidism in which thyroid-stimulating hormone receptor antibodies were found. An 82-year-old female presented with a 1-year history of a large pruritic plaque which was present over both her legs and feet. Histopathology of a skin biopsy showed markedly increased dermal mucin. These changes were suggestive of PTM. This case provides evidence that an autoimmune mechanism could play a central pathogenetic role in such cutaneous manifestations.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed341    
    Printed30    
    Emailed0    
    PDF Downloaded33    
    Comments [Add]    

Recommend this journal