|Year : 2019 | Volume
| Issue : 1 | Page : 56-57
Comment on report of two cases of cutaneous Mycobacterium abscessus infection complicating professional decorative tattoo
Antimicrobial Resistance Research Center; Department of Microbiology and Virology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
|Date of Web Publication||28-Mar-2019|
Department of Microbiology and Virology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
Keikha M. Comment on report of two cases of cutaneous Mycobacterium abscessus infection complicating professional decorative tattoo. Dermatol Sin 2019;37:56-7
|How to cite this URL:|
Keikha M. Comment on report of two cases of cutaneous Mycobacterium abscessus infection complicating professional decorative tattoo. Dermatol Sin [serial online] 2019 [cited 2019 Apr 19];37:56-7. Available from: http://www.dermsinica.org/text.asp?2019/37/1/56/255035
Wu et al. recently published their report on Report of two cases of cutaneous Mycobacterium abscessus infection complicating professional decorative tattoo. Nontuberculosis mycobacteria (NTM) (or atypical mycobacteria) are Gram-positive, acid–fast bacteria which are present in the environmental resources including soil, dust, rivers, lakes, and swamps. Rapidly growing mycobacteria such as Mycobacterium fortuitum, Mycobacterium chelonae, and Mycobacterium abscessus are responsible for a wide spectrum of soft-tissue infections and disseminated infection in immunocompromised patients and healthy individuals.,
Misdiagnosis of mycobacterial infections can be a life-threatening error, especially M. abscessus which is one of the most resistant organisms to chemotherapeutic agents. This bacterium is intrinsically resistant to classical antimycobacterial drugs and most of the antibiotics that are currently available., Detection and identification of NTM is necessary; NTM should be identified at the species level to determine their clinical significance, appropriate treatment, and epidemiological investigations. NTM species are usually identified using phenotypic and molecular methods; phenotypic tests include colony morphology; growth rate; pigment production; growth at 25°C, 37°C, and 42°C; growth on MacConkey agar; urease and niacin production; iron uptake; tellurite and nitrate reduction; tolerance to 5% NaCl; arylsulfatase; heat labile; and heat stable catalase which are cumbersome, labor, time-consuming, often difficult to standardize, and in some cases are confusing, while molecular tests such as direct sequencing and polymerase chain reaction-restriction fragment length polymorphism analysis using housekeeping genes (16S rRNA, hsp65, rpoB, and 16-23S rRNA internal transcribed spacer) are rapid, accurate, and reliable options for identification and differentiation of mycobacteria.,
I request the authors attend to the following questions.
- According to the reports, other geneses in the Actinomycetes family such as Mycobacterium tuberculosis, Nocardia, Rhodococcus, and Gordonia similar to NTM are same phenotypic features; please describe the mycobacterial isolation method, which was not stated in the report
- Please explain how Mycobacterium abscessus was identified to the species level.
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